abstract：:The history and recent developments in label technology are reviewed. Because the new labels generally are used in both classic immunoassays and immunometric assays, a brief review of the advantages and disadvantages of each type of assay is included. Recent developments in enzyme labels, such as channeling techniques...

journal_title：Archives of pathology & laboratory medicine

authors： Howanitz JH

更新日期：1988-08-01 00:00:00

abstract：:Four instances (8%) of inflammatory fibroid polyp (IFP) with concomitant adenocarcinoma or adenoma, in the same area, were noted among 50 cases of IFP of the stomach. Adding two cases from other sources, four cases of gastric IFP concomitant with an adenocarcinoma and two of gastric IFP concomitant with an adenoma wer...

journal_title：Archives of pathology & laboratory medicine

authors： Mori M,Tamura S,Enjoji M,Sugimachi K

更新日期：1988-08-01 00:00:00

abstract：:Chlamydia trachomatis and the genital mycoplasmas are significantly prevalent in sexually active women. How these organisms may affect the outcome of pregnancy and the neonate was the principal thrust of this investigation. Placenta, liver, and lung tissue were cultured from Mycoplasma hominis, Ureaplasma urealyticum,...

journal_title：Archives of pathology & laboratory medicine

authors： Madan E,Meyer MP,Amortegui AJ

更新日期：1988-07-01 00:00:00

abstract：:Reported is an instance of bronchiolitis obliterans due to the accumulation of lipid-laden cells within bronchiolar walls and lumina. The bronchiolar lining had extensive squamous and goblet cell metaplasia with focal ulceration. Scattered foci of cholesterol pneumonia, composed of acicular crystals with an associated...

journal_title：Archives of pathology & laboratory medicine

authors： Heffelfinger SC,Weilbaecher DG,Lawrence EC,Johnson EH,Greenberg SD

更新日期：1988-06-01 00:00:00

abstract：:The efficacy of two new monoclonal antibodies with cell lineage-restricted reactivity (HMB-45 [melanocytes] and anti-synaptophysin [neuroepithelial cells]) was compared with that of "traditional" antibody panels in the delineation of malignant melanoma (MM) of the sinonasal region, nasopharyngeal carcinoma (NPC), and ...

journal_title：Archives of pathology & laboratory medicine

authors： Wick MR,Stanley SJ,Swanson PE

更新日期：1988-06-01 00:00:00

abstract：:We reviewed 36 body fluid specimens from 18 patients with Hodgkin's disease (HD) to characterize the cytologic features of HD as seen in Wright-Giemsa (WG)-stained cytocentrifuge preparations, and to compare diagnostic agreement between WG- and Papanicolaou-stained samples. Slides were examined independently by two pa...

journal_title：Archives of pathology & laboratory medicine

authors： Wilson MS,Theil KS,Goodwin RA,Brandt JT

更新日期：1988-06-01 00:00:00

abstract：:Twenty chordomas from 20 patients, including 17 nonchondroid and three chondroid types, were studied with a variety of antibodies directed against cytokeratin (AE-1/3), epithelial membrane antigen, carcinoembryonic antigen, S100 protein, vimentin, alpha 1-antichymotrypsin, and lysozyme. All 17 nonchondroid chordomas s...

journal_title：Archives of pathology & laboratory medicine

authors： Meis JM,Giraldo AA

更新日期：1988-05-01 00:00:00

abstract：:The clinical and pathologic features of a case of postoperative spindle-cell nodule within the endometrium are reported, a lesion hitherto undescribed in this site. The nodule was found in the hysterectomy specimen from a 75-year-old woman, 2 1/2 weeks after a dilatation and curettage had revealed a well-differentiate...

journal_title：Archives of pathology & laboratory medicine

authors： Clement PB

更新日期：1988-05-01 00:00:00

abstract：:The Health Care Financing Administration of the US Department of Health and Human Services is the federal agency that has the responsibility for the administration of the Medicare and Clinical Laboratories Improvement Act of 1967 programs, including the promulgation of standards for clinical laboratories. The Health C...

journal_title：Archives of pathology & laboratory medicine

authors： Edinger SE

更新日期：1988-04-01 00:00:00

abstract：:The author's long experience as Chairman of the Laboratory Accreditation Program of the College of American Pathologists provides the background for this article. Laboratory accreditation and proficiency testing have now become an established part of the clinical laboratories in the United States. This article attempt...

journal_title：Archives of pathology & laboratory medicine

authors： Duckworth JK

更新日期：1988-04-01 00:00:00

abstract：:Laboratories participating in the College of American Pathologists Enzyme Survey (ES) and Comprehensive Chemistry Survey used diverse methods for the same analyte, resulting in a considerable range of values for the commonly performed enzyme measurements. Nevertheless, with the techniques developed for the ES, both th...

journal_title：Archives of pathology & laboratory medicine

authors： Lott JA,Tholen DW,Massion CG

更新日期：1988-04-01 00:00:00

abstract：:Although it has long been recognized that hyperbilirubinemia is enhanced in patients with impaired renal function, a clear correlation between the levels of bilirubin and creatinine in serum has never been established. We have studied this relationship in 13 bone marrow transplant recipients who had episodes of combin...

journal_title：Archives of pathology & laboratory medicine

authors： Yasmineh WG,Killeen AA,Filipovich AH

更新日期：1988-03-01 00:00:00

abstract：:Previous studies have reported on the pathologic spectrum of perinatal mortality; however, in our opinion, the problems pertaining to the term newborn have not been emphasized sufficiently. We reviewed the autopsies of all term infants up to 2 months of age in a ten-year period (July 1975 to July 1985). These 342 pati...

journal_title：Archives of pathology & laboratory medicine

authors： Rosenthal N,Abramowsky CR

更新日期：1988-02-01 00:00:00

abstract：:Cryptococcus neoformans strains from 26 individual patients with acquired immunodeficiency syndrome (AIDS) and three isolates from patients without AIDS were tested for their susceptibility to amphotericin B, flucytosine, ketoconazole, and miconazole nitrate. Ninety percent of the C neoformans isolates from patients w...

journal_title：Archives of pathology & laboratory medicine

authors： Poon M,Cronin DC 2nd,Wormser GP,Bottone EJ

更新日期：1988-02-01 00:00:00

abstract：:Gene rearrangement analysis has emerged as a precise laboratory aid in the diagnosis and classification of malignant lymphoma and leukemia. Both clonality and lineage can be identified in lymphoid neoplasms by the demonstration of rearrangements of antigen receptor genes of the immunoglobulin supergene family--immunog...

journal_title：Archives of pathology & laboratory medicine

authors： Cossman J,Uppenkamp M,Sundeen J,Coupland R,Raffeld M

更新日期：1988-02-01 00:00:00

abstract：:A skeletal myxoid chondrosarcoma of the femur was examined by light and electron microscopy. Light microscopic features were characteristic for myxoid chondrosarcoma or "chordoid sarcoma." Electron microscopy disclosed crystalline arrays of microtubules within dilated rough endoplasmic reticulum, a feature previously ...

journal_title：Archives of pathology & laboratory medicine

authors： Wolford JF,Bedetti CD

更新日期：1988-01-01 00:00:00

abstract：:Human leukocyte antigen typing is currently being done by both serologic and cellular techniques. It is this methodology that forms the basis for organ transplantation, since HLA antigens are the major proteins involved in graft rejection. Matching organ graft donors with recipients at these polymorphic HLA loci clear...

journal_title：Archives of pathology & laboratory medicine

authors： Freeman SM,Noreen HJ,Bach FH

更新日期：1988-01-01 00:00:00

abstract：:A case of acquired von Willebrand's syndrome associated with an extranodal pulmonary lymphoma is reported in a 58-year-old man. His initial factor VIII-von Willebrand factor (vWF) complex parameters included a factor VIII activity of 29 U/dL, a vWF protein of 17 U/dL, and a ristocetin cofactor of less than 10 U/dL. A ...

journal_title：Archives of pathology & laboratory medicine

authors： Rao KP,Kizer J,Jones TJ,Anunciado A,Pepkowitz SH,Lazarchick J

更新日期：1988-01-01 00:00:00

abstract：:Patients with inherited or acquired immunodeficiency disorders are vulnerable to a broad spectrum of opportunistic infectious diseases, but a narrow spectrum of malignancies. These malignancies--B-cell lymphomas, Kaposi's sarcomas, and squamous cell carcinomas--are likely due to failure of immune surveillance to recog...

journal_title：Archives of pathology & laboratory medicine

authors： Purtilo DT

更新日期：1987-12-01 00:00:00

abstract：:A case of cigarette smoking-related polyclonal B lymphocytosis, with binucleated cells, was observed. The condition was persistent for two years. We indicated the abnormal ultrastructural features and suggest that this unexplained syndrome could be a premalignant state. ...

journal_title：Archives of pathology & laboratory medicine

authors： Casassus P,Lortholary P,Komarover H,Lejeune F,Hors J

更新日期：1987-11-01 00:00:00

abstract：:A T-cell immunoblastic lymphoma having plasmacytoid features that mimic B-cell immunoblastic lymphoma, is described. The lesion was composed of sheets of pleomorphic plasmacytoid cells that displayed a helper T-cell immunophenotype (Leu-1+, Leu-3+, Leu-4+, Leu-5+, Leu-9-, Leu-2-). Ultrastructural features were consist...

journal_title：Archives of pathology & laboratory medicine

authors： Swanson S,Innes DJ Jr,Frierson HF Jr,Hess CE

更新日期：1987-11-01 00:00:00

abstract：:A 50-year-old man presented with a lung mass in the left upper lobe, which was shown by electron microscopy to be a thymoma. There was no evidence of a mediastinal mass. The lymphocytes of the tumor reacted with monoclonal antibody T101, a pan T-cell marker, and with OKT8. B1 and B2 surface antigens characteristic of ...

journal_title：Archives of pathology & laboratory medicine

authors： Green WR,Pressoir R,Gumbs RV,Warner O,Naab T,Qayumi M

更新日期：1987-11-01 00:00:00

abstract：:Nasal mucosal biopsy specimens encompassing normal and pathological epithelia were obtained from nickel workers, a population with an increased incidence of carcinomas of the respiratory tract. The immunohistochemical detection of keratins was carried out using monoclonal antibodies AE1 and AE3. The antibody AE1 stain...

journal_title：Archives of pathology & laboratory medicine

authors： Klein-Szanto AJ,Boysen M,Reith A

更新日期：1987-11-01 00:00:00

abstract：:Myocyte injury in acute cardiac transplant rejection was studied ultrastructurally in 45 patients. Mild myocyte injury consisted of increased glycogen granules and mitochondria, and condensation and streaming of myofilaments. More severe cell injury was characterized by clumping of Z-band material at the periphery of ...

journal_title：Archives of pathology & laboratory medicine

authors： Myles JL,Ratliff NB,McMahon JT,Golding LR,Hobbs RE,Rincon G,Sterba RW,Stewart R

更新日期：1987-10-01 00:00:00

abstract：:The concentration of neuron-specific enolase (NSE, gamma-subunit of enolase) in tumor extracts of 25 nonargyrophilic and seven argyrophilic carcinomas of the female breast was measured by radioimmunoassay. The mean concentration of NSE in nonargyrophilic carcinomas was 89 ng/mg of protein, (range, 9 to 281 ng/mg), and...

journal_title：Archives of pathology & laboratory medicine

authors： Wilander E,Påhlman S,Sällström J,Lindgren A

更新日期：1987-09-01 00:00:00

abstract：:The use of digoxin-specific fragments, antigen-binding (Fab) for antidotal therapy of severe digitalis intoxication is rapidly becoming a treatment of choice. Furthermore, studies with this mode of drug-specific therapy using Fab specific for desipramine and for phencyclidine suggest that this treatment may be applica...

journal_title：Archives of pathology & laboratory medicine

authors： Hursting MJ,Raisys VA,Opheim KE

更新日期：1987-08-01 00:00:00

abstract：:We report a case of "uncombable hair syndrome" that occurred in a boy who had no other abnormalities. The diagnosis was clinically suspected and confirmed by examination of the scalp hair, which was treated with a bath of gold. Scanning electron microscopy was used for examination. The main defect of the hair was a lo...

journal_title：Archives of pathology & laboratory medicine

authors： Zegpi M,Roa I

更新日期：1987-08-01 00:00:00

abstract：:A case of primary fibrosarcoma of the urinary bladder showing extensive chondroid differentiation was studied by light microscopy and immunofluorescent microscopy using tissue-specific antibodies against intermediate filaments. The tumor cells were uniformly and positively labeled with vimentin antibodies and were neg...

journal_title：Archives of pathology & laboratory medicine

authors： Suster S,Huszar M,Bubis JJ,Geiger B

更新日期：1987-08-01 00:00:00

abstract：:The demands for information retrieval, processing, and synthesis placed on all providers of health care have increased dramatically in the last several decades. Although systems have been developed to capture charge-related data in support of cost reimbursement, there has been a conspicuous lack of attention paid to i...

journal_title：Archives of pathology & laboratory medicine

authors： Korpman RA

更新日期：1987-07-01 00:00:00

abstract：:A dyserythropoietic syndrome with coincidental immune thrombocytopenia seen during pregnancy is discussed. The morphological and serological results in this case most resemble type II congenital dyserythropoietic anemia. However, functional evidence of dyserythropoiesis was absent and the patient was not anemic. Splen...

journal_title：Archives of pathology & laboratory medicine

authors： Lillicrap DP,Corbett WE,Giles AR,Ginsburg AD

更新日期：1987-06-01 00:00:00

abstract：:The usual gross appearance of a renal oncocytoma is that of a well-circumscribed homogeneous tan-brown tumor with no evidence of necrosis or hemorrhage, but with a central fibrous scar. We describe a case of renal oncocytoma with the unusual gross appearance of a cystic tumor. While cystic change has occasionally been...

journal_title：Archives of pathology & laboratory medicine

authors： Ogden BW,Beckman EN,Rodriguez FH Jr

更新日期：1987-05-01 00:00:00

abstract：:Three pseudosarcomatous lesions of the genitourinary tract are described. One that arose in the urinary bladder of a 59-year-old man was composed of atypical spindle cells admixed with inflammatory cells in an edematous stroma. The second lesion occurred in the stroma of a hyperplastic prostate gland of a 51-year-old ...

journal_title：Archives of pathology & laboratory medicine

authors： Young RH,Scully RE

更新日期：1987-04-01 00:00:00

abstract：:Discrepancies between the hematocrit values measured by automated methods and those measured by centrifugation have discouraged the use of the centrifuged microhematocrit to calibrate automated hematology analyzers. The discrepancy appears to be due to changes in the internal viscosity of red blood cells and can be el...

journal_title：Archives of pathology & laboratory medicine

authors： Crawford JM,Lau YR,Bull B

更新日期：1987-04-01 00:00:00

abstract：:Data concerning the activities of faculty and various characteristics of academic departments of pathology were obtained from questionnaires returned by 94 chairmen and 1571 faculty members. Data concerning manpower that was the subject of a previous report indicated that the projected supply of MD pathologists for fa...

journal_title：Archives of pathology & laboratory medicine

authors： Smith RD,Anderson RE,Benson ES

更新日期：1987-04-01 00:00:00

abstract：:Malignant mixed müllerian tumor of the fallopian tube is an extremely rare neoplasm, with less than 30 cases reported. Clinical signs and symptoms are usually nonspecific and include lower abdominal pain, fever, and vaginal bleeding. The age at diagnosis varies from 14 to 76 years, with a mean of 55 years. Prognosis i...

journal_title：Archives of pathology & laboratory medicine

authors： Buchino JJ,Buchino JJ

更新日期：1987-04-01 00:00:00

abstract：:Myocardium as emboli is a decidedly rare phenomenon. Only three such examples were identified among 8033 consecutive autopsies performed over a ten-year period, 1976 to 1985, an incidence of 0.037%. In two of these three cases, myocardial emboli occurred in the systemic (coronary) circulation. The source of emboli was...

journal_title：Archives of pathology & laboratory medicine

authors： Lie JT

更新日期：1987-03-01 00:00:00

abstract：:We report two cases of primary cardiac lymphoma that developed in patients suffering from the acquired immunodeficiency syndrome. Both cases of lymphoma were histologically aggressive as generally observed in patients with the acquired immunodeficiency syndrome. The lymphoma cells in the center of a tumor nodule obtai...

journal_title：Archives of pathology & laboratory medicine

authors： Guarner J,Brynes RK,Chan WC,Birdsong G,Hertzler G

更新日期：1987-03-01 00:00:00

abstract：:The prune belly syndrome is a well-recognized entity consisting of deficient abdominal musculature, cryptorchid testes, and urinary tract abnormalities most consistent with an obstructive phenomenon. However, an obstructive lesion has not been consistently identified in previously reported cases. Retrospective review ...

journal_title：Archives of pathology & laboratory medicine

authors： Hoagland MH,Hutchins GM

更新日期：1987-02-01 00:00:00

abstract：:Distinctive morphological features in both the marrow infiltrate and the kidney were seen in a 52-year-old woman with kappa light chain-producing plasma cell myeloma, diagnosed on the basis of multiple osteolytic lesions, the presence of atypical plasma cells in the bone marrow, and monoclonal immunoglobulin productio...

journal_title：Archives of pathology & laboratory medicine

authors： Chan KW,Ho FC,Chan MK

更新日期：1987-02-01 00:00:00

abstract：:We present a case of non-Hodgkin's lymphoma with massive cardiac involvement in a previously well 65-year-old man, presenting with pericardial tamponade and heart failure of recent onset. Results of echocardiography and of pericardial and pleural fluid cytology suggested the diagnosis. Within two weeks the patient's c...

journal_title：Archives of pathology & laboratory medicine

authors： Cairns P,Butany J,Fulop J,Rakowski H,Hassaram S

更新日期：1987-01-01 00:00:00